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Recent large-scale studies indicate that acetaminophen (Tylenol) use during pregnancy is not associated with a clinically significant increased risk of autism in children when familial and genetic confounding is properly controlled. While some population-based analyses show a very small increase in absolute risk (e.g., 0.09% higher at 10 years), sibling-controlled models-which account for shared genetics and environment-show no association between acetaminophen exposure and autism risk. These fi
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