Integrated polygenic risk scores can help estimate the genetic risk for 8 cardiovascular diseases and conditions.

New methods of analysis and novel markers are currently being identified to predict conditions with polygenic inheritance. These include polygenic risk scores (PRS), which are based on the presence of ...

An insightful mini-review published in Genomic Psychiatry synthesizes the rapidly expanding landscape of molecular genetic research on common epilepsies, assembling evidence from genome-wide ...

A polygenic risk score was able to detect a high proportion of clinically significant prostate cancer. Cancer would not have been detected in 71.8% of patients with the use of PSA or MRI screening.

A new international study challenges the century‑old dominance of Mendelian genetics, arguing that most traits arise from ...

Survey reveals nearly three-quarters of U.S. adults support using emerging technology to screen embryos during IVF for risk of developing certain health conditions or traits that arise from more than ...

Considerable progress has been made in uncovering common single nucleotide variants and developing mechanisms for genomic profiling. Using this knowledge routinely as part of clinical and public ...

Individuals who carry common genetic variants associated with autism tend to have lower density in the brain’s microscopic wiring, regardless of whether they actually have an autism diagnosis. The ...

Role of Apparent Diffusion Coefficient Map-Based First- and High-Order Radiomic Features for the Discrimination of Sacral Chordomas and Chondrosarcomas With Overlapping Conventional Imaging Features ...

Cost-utility studies provide critical information for the costs and benefits of using any new test, typically building on existing public health and screening programmes, within a defined population.