Tooth root development relies on precise coordination of cellular signals, yet the underlying mechanisms remain unclear. Researchers have uncovered how two proteins, Gli2 and Gli3, work together to ...

This summer, over 50 researchers in the NSF EMBRIO Institute convened to share their newest findings on cellular signaling and organization that drives wound repair, cellular defense, and organismal ...

Signaling is fundamental to how cells sense and respond to their environment—but in immune cells, those signals must be ...

A hormone that reverses obesity in mice appears to work by signaling to a brain region involved in metabolism and appetite ...

Antimicrobial resistance (AMR) poses a major global health challenge by compromising the effectiveness of current therapies for infectious diseases. While ...

In a major brain science breakthrough, New Orleans-based researchers and collaborators have discovered a nerve signaling mechanism that takes place outside the cell, flipping on a 'pain switch.' This ...

Peptide science has expanded rapidly in recent decades, revealing molecules with intriguing signaling roles that may influence diverse regenerative and organizational processes within an organism.

Orthodontic treatment relies on the biological response of periodontal and alveolar bone tissues to mechanical forces, which induces tooth movement through ...

Cellular differentiation of stem cells into specialized cells requires many steps, including division, to create more cells; fate determination, which is a commitment to a specific lineage or ...