Checkpoint inhibitors are a groundbreaking class of cancer treatment, but they come with two frustrating challenges. In some cases, tumors show no initial response, rendering the therapy ineffective ...

“Interestingly, BIRC5 and MCL-1 have both been reported to be over-expressed and strongly correlated with progression and ...

Accurate information and leadership buy-in are essential. The researchers noted three types of resistance that are common are denying, defending and distancing. One of the strategies suggested by ...

Two companion studies published in Cancer Research by scientists at Moffitt Cancer Center identify distinct but complementary approaches to overcoming drug resistance in KRAS G12C-mutant non-small ...

Panelists discuss how overcoming resistance to EGFR TKIs requires next-generation inhibitors and more individualized treatment strategies. Panelists discuss how resistance to EGFR tyrosine kinase ...

Epithelioid sarcoma, a rare aggressive cancer that usually strikes young adults, and rhabdoid tumors, which affect children, have long been difficult to treat. But the outlook for people with these ...

Antimicrobial resistance (AMR) towards medicine has been an ongoing concern for the last several decades. The concept that a microbe can build resistance and multiply faster than scientists can find a ...

In recent years, we’ve seen tremendous growth in diversity, equity, and inclusion initiatives. Many people have eagerly embraced these efforts, but some have criticized and resisted them, including ...

Staphylococcus aureus has the potential to develop durable vancomycin resistance, according to a new study. Staphylococcus aureus has the potential to develop durable vancomycin resistance, according ...

Two companion studies published in Cancer Research from scientists at Moffitt Cancer Center identify distinct but complementary approaches to overcoming drug resistance in KRAS G12C–mutant non-small ...

Resistance—the pushback we feel when facing change—isn’t a flaw; it’s data. It signals unmet needs, unprocessed fears, or a lack of clarity. Why do we hesitate, avoid, or resist what’s ahead? With ...

It’s the foundation for overcoming resistance, and it’s a vital skill I now teach to leaders in healthcare, education, and beyond. Here are the steps I took—and that you can take—to navigate ...