Case Western Reserve University researchers have taken a dramatic step forward in the fight against cancer—all by starting at the very beginning. Scientists led by School of Medicine Professor Mark W.

Dr. Bishop shared a Nobel Prize with Harold Varmus for his work on cancer-causing genes called oncogenes. He later served as ...

Extrachromosomal DNAs (ecDNAs) are circular DNA structures located in the nuclei of cells outside chromosomes. They were originally discovered in chromosome spreads of cells obtained from embryonal ...

Perioperative therapy has become a critical component in the management of resectable non–small cell lung cancer (NSCLC), particularly in the era of precision medicine. Although molecular testing is ...

Boundless Bio (Nasdaq: BOLD), a clinical-stage oncology company interrogating extrachromosomal DNA (ecDNA) biology to deliver transformative therapies to patients with previously intractable oncogene ...

ctDNA clearance within 10 weeks of TKI treatment initiation correlates with improved OS and PFS in advanced NSCLC patients. ctDNA is emerging as a promising early biomarker for predicting clinical ...

“Our findings suggest that increase expression levels of Derlin1 and PSMD10 genes in HeLa cells by the EBV-EBNA1 might induce cancer cell survival and accelerates the development of cervical cancer ...

Pancreatic cancer remains one of the deadliest cancers, with survival rates showing little improvement over decades and projections placing it as the second leading cause of cancer deaths by 2030.

Karan Arora, senior vice president of advanced assays, AI, and pharma services at Leica Biosystems outlines the critical role diagnostics have to play in unlocking the promise of precision medicine.