The gold-standard treatment for patients with chronic anal fissure (CAF) is lateral internal sphincterotomy (LIS). Few studies have assessed the impact of this procedure with regard to quality of life ...

How do you treat a recurrent anal fissure, 6 months after adequate lateral sphincterotomy? The patient is a 65-year-old, markedly obese man with no evidence of inflammatory bowel disease. An anal ...

The management of chronic anal fissure has received renewed interest and has been re-evaluated over the past 20 years. The use of botulinum toxin seems to be a promising and safe approach, ...

A 2012 Cochrane systematic review (assessed as up to date September 2011, Nelson et al. 2012) investigated non-surgical therapy for anal fissure. A second systematic review of clinical trials ...