Inspired by hepatic lobules, a novel artificial liver was developed by assembling morphological cell sheets with high accuracy in terms of cell type, density, and distribution. By simulating the ...

Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers have now determined that ...

Subtle cellular interactions, especially involving immune cells and lipid metabolism, are crucial in MASH progression. A spatially resolved, multi-omics atlas of MASLD was developed, integrating ...

The liver is often called a "silent organ," as it can sustain significant damage without obvious symptoms. But when injury is ...

A high-resolution cellular atlas of liver fibrosis and recovery identifies two proteins, SEMA4D and LMCD1, as promising ...