Challenging the long-standing belief that fibroblasts produce skin collagen, researchers have investigated collagen formation in the 'glass-skinned' amphibian axolotl and other vertebrates. They ...

Investigating collagen peptides, this review explores their role in skin aging, assessing clinical evidence and the ...

A working model showing that CAFs exhibit profound amino acid reprogramming, especially the production of glycine, in CRC. CRC cell‐derived TGF‐β1 activates de novo glycine synthesis in CAFs, ...

Hypertrophic scarring affects a large proportion of patients following burns, trauma, or surgery and arises from prolonged fibroblast hyperactivity and excessive extracellular matrix accumulation.

Evaluation of the hedgehog signaling pathway as a therapeutic target for dendritic cell-based immunotherapy against patients with cancer. Background: Activated fibroblasts in the stroma of epithelial ...

Rob Erskine does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their ...

Axolotl is an animal model widely used in dermatology research due to its transparent ‘glass skin.’ A study by researchers from Okayama University, Japan, discovered that healthy collagen fibers, ...