The discovery challenges the long-standing idea that early humans mainly evolved and survived in open grasslands, coasts, or other less demanding environments.

When it comes to cancer, tumor suppressor genes are usually thought of as the "good guys." These genes make proteins that ...

Scientists at Children's Medical Center Research Institute at UT Southwestern (CRI) have discovered that large pieces of DNA ...

In a recent study published in the journal Nature, researchers found that the recruitment of neurons to memory circuits is preceded by a cascade of molecular events induced during learning, which ...

Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in nuclear DNA. These lesions disrupt energy production and activate ...

For decades, oncologists have watched a frustrating pattern repeat itself. Tumors fueled by the MYC protein, one of the most ...

RNA Polymerase (shown in blue) moves across a template strand of DNA (shown in purple) and transcribes it into RNA (shown in red). But DNA damage blocks the RNA polymerase, causing it to stall and ...

Researchers have identified a pathway that triggers an immune response in cells with defective DNA repair. In particular, the ...

The study focused on rare DNA damage-repair (DDR) disorders, including Ataxia-Telangiectasia (A-T) and Bloom syndrome. These conditions disrupt the body’s ability to repair routine DNA damage, causing ...

A protein best known for driving cancer growth also helps damaged tumor cells survive by repairing their DNA, according to a ...

A new study suggests the APOE2 longevity gene may protect the brain from Alzheimer's by helping neurons repair DNA damage and resist cell aging.