Researchers from Amsterdam UMC have overturned a key assumption in the biological pacemaker field. In a new preclinical study, they show that the transcription factor TBX18 does not generate true ...
Scientists from the McEwen Centre for Regenerative Medicine, University Health Network, have developed the first functional pacemaker cells from human stem cells, paving the way for alternate, ...
GUADALAJARA, Mexico — "Somatic reprogramming is a strategy in which we are not modifying a single part of the cell, but we are reprogramming a normal cell to transform it into a pacemaker cell," said ...
With a new $3 million grant from the National Institutes of Health, Cedars-Sinai Heart Institute investigators are moving closer to their goal of developing a biological pacemaker that can treat ...
A multidisciplinary research team has revealed that the circadian clock -- the biological pacemaker that governs daily rhythms in physiological processes, including immune functions -- can be ...
WASHINGTON (AP) — No batteries required: Scientists are creating a biological pacemaker by injecting a gene into the hearts of sick pigs that changed ordinary cardiac cells into a special kind that ...
Electrical pacemakers have become a backbone in therapeutic intervention for slow heart rhythms resulting from conduction system disease. Although decades of innovations have greatly improved the ...
WASHINGTON (Reuters) - Researchers have succeeded in turning ordinary cardiac muscle cells into specialized ones that deliver a steady heartbeat using a gene therapy procedure they predict could ...
For more than a decade, TBX18 has been reported to reprogram working ventricular cardiomyocytes into sinoatrial‑node–like pacemaker cells, based on widely cited high‑impact papers. Using low ...