The vast majority of cancer cells have too few or too many copies of some chromosomes, a state known as aneuploidy. But for decades, researchers have debated whether aneuploidy promotes the growth of ...
The mitotic checkpoint is a major cell cycle control mechanism that acts to guard against chromosome missegregation and the subsequent production of aneuploid daughter cells. Aneuploidy is a ...
What makes cancer cells different from ordinary cells in our bodies? Can these differences be used to strike at them and paralyze their activity? This basic question has bothered cancer researchers ...