A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl group (C=O) to a nitrogen atom. They're so ubiquitous that 117 of the top ...
Amide bonds are among the most ubiquitous linkages in natural products, pharmaceuticals and polymers, yet their inherent resonance stabilisation renders them remarkably inert to conventional reaction ...
Takeaway 3: The Alcohol-to-Amide Shortcut The team extended their logic to create a "one-pot" enzymatic cascade that starts from broadly available aliphatic alcohols. This chemoenzymatic strategy is ...
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Amide Technologies, a biotech that synthesizes challenging peptides, announced today that it has begun commercializing its novel peptide manufacturing platform. The ...
Researchers at the Biocatalysis group led by Dr Francesco Mutti at the Van ‘t Hoff Institute for Molecular Sciences (University of Amsterdam) have developed a novel use of alcohol dehydrogenase (ADH) ...
Even though amide bonds are everywhere—they hold proteins together and are essential components in many drugs—forging this molecular motif in a reaction flask can be challenging. For example, making ...
Polymers are one of the most important elements of modern-day society, particularly in the form of plastics. Unfortunately most common polymers are derived from fossil resources, which not only makes ...
Amide Technologies has raised $16.5 million in venture capital to help commercialize its peptide production process. The process was developed from 2011 to 2017 in the lab of the Massachusetts ...
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